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Who Is This For?

  • ✓ Fine tissue-paper-like texture on neck, decolletage or under-eyes
  • ✓ Eyelid or under-eye skin has become thin and crepey
  • ✓ Hands or inner arms show fine folding skin
  • ✓ You are post-menopausal or in the perimenopausal transition and notice accelerated skin thinning
  • ✗ Primary concern is laxity or sagging — related but different — see Skin Laxity
  • ✗ Surface dryness rather than structural thinning — see Dull Skin

Looking for pricing and booking? Visit our NeoGen treatment page

In Short

  • Crepey skin is driven by elastin loss — distinct from laxity and from surface dehydration.
  • NeoGen PSR is the standout treatment and one of the only technologies able to safely treat the upper eyelid.
  • Polynucleotides and Profhilo are valuable supporting treatments especially in perimenopausal patients.
  • Prevention through SPF 50 and consistent skincare significantly reduces the rate of crepey change.

What Causes It?

  • Elastin loss — the protein allowing skin to recoil; once significantly reduced, the skin folds and does not spring back.
  • Collagen thinning — the dermis becomes structurally thinner and less dense.
  • Hormonal changes — oestrogen directly supports elastin; its decline in perimenopause significantly accelerates crepey change.
  • Chronic UV exposure — the primary environmental driver of elastin breakdown.

Treatments That Help

What Will Not Help

  • Standard fillers — not appropriate for crepey texture; in delicate areas can worsen appearance.
  • Moisturisers alone — support the barrier but cannot reverse elastin loss.

Your Treatment Pathway

ConsultationElastin and tissue quality assessmentPolynucleotides or Profhilo started (tissue preparation)NeoGen PSR course where appropriate — 1 to 3 sessionsMaintenance skincare SPF plus retinolAnnual NeoGen maintenance session

Frequently Asked Questions

Can crepey skin actually be reversed?

Meaningful improvement is achievable — NeoGen PSR stimulates deep collagen and elastin remodelling and the skin becomes noticeably more textured and resilient. Complete reversal to young skin is not realistic but significant improvement in quality and appearance is.

Is NeoGen painful?

The sensation is a warm tingling or mild prickling. Most patients find it very tolerable. Topical anaesthetic is available for sensitive patients.

How long is NeoGen recovery?

The skin bronzes over 7-14 days and the bronzed layer flakes naturally. Social downtime varies by package. Full collagen remodelling results develop over 3-6 months.

Can polynucleotides treat crepey eyelid skin?

Polynucleotides can improve the quality and resilience of periorbital skin. For upper eyelid crepiness, NeoGen PSR is the primary treatment of choice — it is one of the few technologies that can safely treat that area.

How many NeoGen sessions are needed?

One session produces noticeable improvement. A course of three produces the most significant results, spaced 6-8 weeks apart.

Related Concerns

Skin concerns often overlap. You may also find these pages helpful:

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Unsure Which Treatment Is Right?

Comparing NeoGen with other options for crepey skin?

Further Reading – Dr Halliday’s Clinical Guides

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